Two World Health Organization collaborating centres in Brazil have played a central role in strengthening efforts to detect and control leprosy and other skin-related neglected tropical diseases across the Americas, contributing technical expertise to the implementation of the Global Leprosy Strategy 2021–2030.

The collaboration involves the Instituto Lauro de Souza Lima and the Fundação Hospitalar Alfredo da Matta, both recognized by WHO for their specialized work in leprosy and dermatological neglected tropical diseases. Their support has focused on improving diagnosis, laboratory confirmation and case management of diseases including leprosy, cutaneous leishmaniasis and sporotrichosis, alongside other dermatological conditions of public health importance.

According to WHO, the two institutions provided highly specialized clinical and laboratory expertise through subregional and national trainings, workshops and dermatological campaigns aimed at strengthening frontline health systems. Physicians, laboratory technicians and other health personnel participated in practical, case-based training designed to improve early detection and diagnostic accuracy.

The centres introduced updated diagnostic algorithms, laboratory protocols and hands-on mentoring during field activities, helping countries improve referral systems between primary care services and specialist centres. WHO said this contributed to earlier detection, shorter diagnostic delays and stronger continuity of care for affected patients.

The work forms part of WHO’s broader Global Leprosy Strategy 2021–2030, which aims to accelerate progress toward zero leprosy, reduce disability caused by delayed diagnosis and interrupt transmission through earlier case identification and stronger surveillance systems.WHO said its own role focused on strategic coordination, ensuring that technical activities aligned with regional and global health frameworks.

The agency used its convening authority to mobilize ministries of health and partners while integrating the work into wider neglected tropical disease and communicable disease elimination strategies.It also oversaw systematic monitoring and documentation to ensure activities remained consistent with WHO standards and reporting mechanisms.

The organization described the arrangement as a combination of normative leadership and operational expertise, allowing field implementation to move beyond policy planning into practical delivery.“The centres’ technical capacity at country level accelerated progress toward elimination targets and strengthened credibility and responsiveness to national requests,” WHO said in its March 27 feature report.

WHO noted that while coordination could have been managed independently, implementation would have been significantly more limited without the specialized expertise of the collaborating centres, and much of the work would have remained theoretical rather than operationally effective.

A major lesson from the programme was the effectiveness of integrated skin screenings, where multiple dermatological conditions are assessed through a single clinical approach rather than disease-specific interventions.WHO said combining screenings for leprosy, cutaneous leishmaniasis, sporotrichosis and other skin-related neglected tropical diseases reduced stigma for patients and improved service uptake, particularly in vulnerable communities where fear of diagnosis often delays treatment.

The approach also strengthened the broader strategy of using skin examination as an entry point for neglected tropical disease control, allowing healthcare workers to identify multiple conditions through a unified platform.Through a series of national and subregional workshops and campaigns, countries across the Region of the Americas were able to reinforce diagnostic capacity and improve laboratory confirmation of suspected cases.

WHO said these activities helped standardize training materials in line with its global guidelines while increasing awareness among frontline workers about integrated management approaches.The collaborating centres also supported the development of stronger regional networks among clinicians and laboratory professionals, helping create a more coordinated technical community across borders.

This regional harmonization was seen as particularly important for countries with limited specialist capacity, where access to standardized protocols and technical cooperation can directly influence case outcomes.The programme’s outcomes align with the broader targets of the WHO Neglected Tropical Disease Road Map, which seeks to reduce the burden of neglected diseases through prevention, early diagnosis and integrated service delivery.

WHO said the collaboration directly supported programme objectives by accelerating early detection and contributing to interruption of transmission, moving countries closer to elimination milestones.Leprosy remains a public health concern in several parts of the Americas despite significant reductions in prevalence over recent decades.

According to WHO’s January 2026 leprosy fact sheet, continued delays in diagnosis remain one of the major barriers to elimination, particularly where health systems lack specialized diagnostic capacity.Cutaneous leishmaniasis and sporotrichosis also continue to present challenges in endemic areas, particularly among vulnerable populations with limited access to specialist dermatological care.

WHO said the collaboration offers further opportunities for expansion, particularly by extending integrated skin neglected tropical disease approaches to additional countries and developing multilingual regional training curricula through digital platforms.

There is also scope to deepen operational research on early detection strategies and strengthen laboratory networks across the region, particularly in underserved settings where diagnosis remains inconsistent.The organization said the experience in Brazil demonstrates how combining global strategy with country-level technical expertise can improve implementation and strengthen health systems beyond individual disease programmes.

By linking specialized dermatological knowledge with WHO’s policy coordination role, the partnership has become a model for how collaborating centres can support disease elimination efforts while building sustainable regional capacity.

Australia has become the 30th country to eliminate trachoma as a public health problem, with the World Health Organization confirming that the infectious eye disease, once a major cause of preventable blindness in remote Indigenous communities, no longer poses a national public health threat.

The WHO validation marks the first time Australia has been officially recognized for eliminating a neglected tropical disease, placing it among 63 countries globally and the 16th in the Western Pacific region to have eliminated at least one such disease.

Trachoma is caused by the bacterium Chlamydia trachomatis and remains the world’s leading infectious cause of blindness. It spreads through close contact with infected individuals, contaminated surfaces, and flies carrying eye and nasal discharge. Repeated infections can scar the eyelids, causing eyelashes to turn inward and scratch the eye surface, eventually leading to irreversible blindness if left untreated.

WHO Director-General Tedros Adhanom Ghebreyesus said Australia’s achievement represented a major milestone both for Indigenous health outcomes and for global neglected tropical disease control efforts.“WHO congratulates Australia on this important achievement,” Tedros said in a WHO statement.

“This success reflects sustained commitment, strong partnerships, and a focus on reaching populations most affected by health inequities. It brings us closer to a world free from the suffering caused by trachoma.”Australia had eliminated trachoma from most of the country decades ago, but the disease persisted in remote Aboriginal and Torres Strait Islander communities, particularly in areas facing overcrowded housing, poor sanitation, and limited access to clean water and health services.

National efforts intensified in 2006 with the launch of the National Trachoma Management Programme, which adopted the WHO-recommended SAFE strategy: surgery for trichiasis, antibiotics to treat infection, promotion of facial cleanliness, and environmental improvement.

The program included regular screening of all communities classified as at risk, carried out by qualified health workers, alongside treatment and prevention campaigns delivered through cooperation between federal and state governments, Aboriginal Community Controlled Health Organisations, and local communities.

Unlike many countries where mass drug administration formed the main strategy, Australia adapted its response using targeted treatment based on community-level data and stronger integration with housing, sanitation and environmental health programs.WHO said sustained investment in screening, treatment, housing improvements, water access, sanitation and hygiene contributed to a steady decline in disease prevalence over time.

Australia’s Minister for Health and Ageing, Mark Butler, said the validation was particularly significant for communities that had carried the burden of a preventable disease for generations.“Elimination of trachoma is a win for the eye health of communities across Australia, particularly those whose lives have been impacted by a disease that is entirely preventable,” Butler said.

He said Aboriginal and Torres Strait Islander leadership had been central to the outcome, alongside long-term public investment and local health delivery.“The lessons from this work will inform how we approach other preventable health conditions in remote and regional Australia,” he said.

“Aboriginal Community Controlled Health Organisations and local health workers have been central to this success, delivering culturally safe care and community-led solutions.”

Malarndirri McCarthy, Minister for Indigenous Australians, said the recognition reflected decades of work led by First Nations health services rather than a short-term intervention.“This recognition from the World Health Organization reflects decades of work led by Aboriginal Community Controlled Health Organisations, alongside local health workers in remote First Nations communities,” McCarthy said.

“Their work has been critical to eliminating trachoma as a public health problem in Australia.”Trachoma is one of 21 diseases and disease groups classified by WHO as neglected tropical diseases, or NTDs. These diseases collectively affect more than one billion people worldwide, primarily among underserved populations with limited access to clean water, sanitation and essential health care.

WHO said Australia’s achievement demonstrated that elimination was possible even in geographically isolated and logistically difficult settings, provided political commitment and cross-sector coordination were sustained.

Saia Ma’u Piukala, WHO Regional Director for the Western Pacific, said countries across the region face similar challenges in reaching remote populations.“Tackling neglected tropical diseases in the Western Pacific Region has long been a challenge for countries across the socioeconomic spectrum,” Piukala said.

“But I also know that with strategic commitment underpinned by optimal resources and partnerships in health, success is possible.”He urged continued vigilance to ensure Australia maintains elimination status through strong surveillance and integration of monitoring systems into national healthcare structures.

WHO defines elimination of trachoma as a public health problem using three criteria: trachomatous trichiasis prevalence of less than 0.2% among adults aged 15 and above, trachomatous inflammation prevalence of less than 5% among children aged one to nine in formerly endemic districts, and a functioning system to identify and manage new trichiasis cases.

The global effort to eliminate trachoma dates back to 1996, when WHO launched the Alliance for the Global Elimination of Trachoma by 2020, known as GET2020. Although the original target year was missed, WHO’s current roadmap for neglected tropical diseases has extended the goal to 2030.

Australia now joins countries including India, China, Pakistan, Saudi Arabia, Nepal and Viet Nam among those validated by WHO for eliminating trachoma as a public health problem.Despite the success, Australia still faces several other endemic neglected tropical diseases, including Buruli ulcer, leprosy and scabies.

WHO said continued surveillance would remain essential to ensure trachoma does not re-emerge, particularly in vulnerable remote communities where access to services remains uneven.

The organization added that maintaining gains would depend on keeping surveillance systems active, integrating eye health into broader national health planning, and ensuring that improvements in housing, sanitation and healthcare access continue beyond disease elimination targets.